Manhattan’s South Street Seaport has a mission: to become New York City’s coolest new neighborhood. The historic district at the bottom tipof the island—lined with cobblestone streets and located at the apex of Lower Manhattan and the East River—has lately procured reason after reason for tourists (and, yes, even a few locals) to venture south, from new fashion boutiques (like the just-opened 10 Corso Como) to premier waterfront venues. Now, the developing district is ready for overnight guests thanks to the August opening of Mr. C Seaport.

Mr. C Seaport is the careful work of the fourth-generation Cipriani brothers, Maggio and Ignazio, whose family owns and operates the Cipriani restaurant empire, as well as another Mr. C hotel in Beverly Hills. The Bellini was, of course, created by the brothers’ great-great-father, the legendary Giuseppe Cipriani, at Harry’s Bar in Venice, Italy. Both the new Manhattan hotel and that long-beloved beverage of peach of Processo are equally sweet. Putting a modern and polished twist on classic European style, the Mr C was designed by Danish architect Thomas Juul-Hansen, who incorporated nautical touches and sleek, Italian glamour into the 66 rooms and grand public spaces.