Frank Di Piero was born in Chicago and is 100% Italian origin. He has traveled to Italy many times and attended two study abroad programs in Italy, one in Roma and one in Firenze. He is the former President of The Harlem Avenue Italian & American Business Association and was on the committee to start an Italian American Studies Program at Loyola University Chicago. He is a Director of Casa Italia, and LITTLE ITALY Cenetta.

He is on the committee of the Festa della Repubblica celebrated at Pompeii Church. He is a Chicago area representative of C.T.I.M., Comitato Tricolore per gli Italiani nel Mondo. He is a volunteer at Casa Italia Library and the Italian Cultural Center. He is a member of the Italian Catholic Federation, Chicago Branch 392. He is the former Sergeant at Arms of the J.C.C.I.A.