The Abruzzo, Lazio, and Molise National Park, until recently known just as the Abruzzo National Park, is an Italian national park with headquarters in the town of Pescasseroli (population 2,206 in the 2015 census) in the province of L’Aquila in the region of Abruzzo. It is the oldest national park in the Apennine mountains and the second oldest in Italy.

The idea for the creation of the park came from Erminio Sipari (1879-1968), a member of the Italian Parliament from the province of Frosinone in the region of Lazio. During October and November 1921, the community of Opi in the province of L’Aquila leased five square kilometers of land to a private federation to protect its flora and fauna.