A landlocked region between Tuscany, Lazio, and Le Marche, Umbria often gets overlooked by travelers allured to its much-hyped surroundings – especially Tuscany. But cognoscenti know that Umbria shouldn't be skipped  – there, it's easy to feel at one with the world and with Italy. In addition to the picturesque unspoiled landscapes, the tranquility, and hearty, earthy cuisine, the region is abuzz with some noteworthy movers and shakers. 

It seems that during the Pleistocene epoch, which started 2.6 million years ago and lasted until about 11,700 years ago, the leptobos lived in Umbria. This bovid genus is believed to be the bison's ancestor, as evidenced by the femur exhibited at the Paleontological Museum of Pietrafitta in the province of Perugia.